Aging and diseases of the circulatory System

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Aging and diseases of the circulatory System

Aging and diseases of the circulatory System


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Aging and diseases of the cardiovascular system: a growing challenge for the company The man in years, and only change the circumstances of his life — the body is subject to irreversible processes. One of the most important aspects of the aging affects the cardiovascular System for the supply of all organs with oxygen and nutrients responsible. With increasing age, the risk of diseases of this system increases dramatically and thus the burden on the health care system. Dieatomische changes in the age From the 30. Years old begin to change the blood vessels slowly. The arteries lose their elasticity, their walls thicken, a process known as atherosclerosis. This calcification of the vessels leads to the fact that the heart must work to pump the blood through the body. At the same time, it can lead to Plaques (deposits) in the walls of blood vessels, restricting the blood flow and in the worst case to a closure. Also, the heart muscle tissue itself is changing: It is slowly losing its power, the pump power decreases. This is particularly critical high blood pressure, if additional risk factors — for example, Diabetes, Obesity, or nicotine abuse. Common diseases in old age Among the most common diseases of the cardiovascular system in older people: Coronary heart disease (CHD): By narrowing of the heart arteries the blood supply to the heart muscle is affected. Symptoms such as chest pain (Angina) or a heart attack can result. Congestive heart failure: The heart loses its pumping efficiency, resulting in fluid in the legs or in the lungs can ansammlen. Arrhythmias: heart rhythm disorders, in particular atrial fibrillation, occur with increasing age, more frequently and increase the risk of stroke. High blood pressure (hypertension): A permanently elevated blood pressure is damaging in the long term, heart, and vessels and is a major risk factor for stroke and heart attack. Prevention: What can you do? Dieuch if the aging is a natural process, the risk for cardiovascular diseases is significantly lower. Important measures are: Regular physical activity: walking, Swimming or Cycling, strengthen the heart and keep the blood vessels elastic. A balanced diet: Plenty of vegetables, fruits, fish and fibre, low in salt and saturated fatty acids, which lowers the level of cholesterol and blood pressure. Waiver of Smoking: nicotine harms the inner vessel walls and promotes atherosclerosis. Regular checkups: measurement of blood pressure, cholesterol and blood sugar checks help to identify risks at an early stage. Stress management: Chronic Stress is hard on the heart — relaxation techniques such as Yoga or Meditation can be helpful here. Conclusion The lady of the cardiovascular system, no fate, but a process that can be influenced by conscious lifestyle in a positive way. The earlier one is preventive, the higher the chances the higher the age of a healthy and active life. Socially, it is also important for the prevention and early detection of cardiovascular diseases and continue to grow because it is only the growing burden on the health care system in the long term to cope with.

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The pathogenesis of cardiovascular diseases: A view into the depth of the human system This is below the world and the lifestyle of people is changing, the prevalence of cardiovascular disease (CVD) worldwide. These diseases are among the leading causes of death and represent a serious challenge for the health system. But what exactly is in the body the wrong way, if such a condition develops? What are the mechanisms behind the pathogenesis of this life-threatening conditions? The basis of many cardiovascular diseases is often a combination of genetic predisposition and environmental influences. The pathogenesis of the disease usually begins with subtle changes in the vascular system — for example, with the formation of atherosclerosis plaques. These Plaques are caused by the deposition of lipids, in particular LDL‑cholesterol in the Intima of the arteries. The process works as follows: Endothelial damage. The endothelium — the inner lining of the blood vessels caused by factors such as increased blood pressure, Smoking, hyperglycemia, or inflammatory processes. Lipid storage. LDL particles to penetrate into the vessel wall and become oxidized. This is a local inflammatory response triggers. Immune response. Macrophages migrate to the sites of Injury and to phagocytize the oxidized lipids. You transform into foam cells, the part of the picture ends Plaque. Plaque formation and progression. The Plaque grows and can restrict the vascular Lumina. In later stages it can lead to cracking of the Plaque, which leads to thrombus formation. Consequences for the cardiovascular System. Due to the restriction of blood flow to Ischemia — for example a heart attack or stroke. In addition to atherosclerosis, further pathophysiological mechanisms play a role: High Blood Pressure (Hypertension). Due to increased vascular resistance and increased cardiac output, an Overload of the heart arises. In the long term, this leads to left heart enlargement and congestive heart failure. Inflammatory processes. Chronic inflammation, such as obesity or type 2 Diabetes mellitus, promote the development and Progression of CVD. Metabolic disorders. Insulin resistance and dyslipidemia create an environment in which vascular damage may occur easier. Prevention as the key to combating The findings on the pathogenesis of the show: Many of the risk factors can be influenced. A healthy diet, regular physical activity, the lack of Smoking, and stress management can slow down the development of cardiovascular diseases significantly or even prevent it. Medical diagnosis — for example, by measurement of blood pressure, cholesterol tests and blood sugar controls — makes it possible to identify high-risk patients at an early stage and to take care of specifically. Conclusion The pathogenesis of cardiovascular diseases is a complex, multi-stage event that occurs on a molecular, cellular and systemic level. But just because we now know so much about these processes, we have effective tools to prevent disease and mitigate its effects. The future is, therefore, not only therapy, but, above all, the prevention for a healthier life and a healthier society. If you want, I can make a specific section in more detail, or to install additional aspects (such as specific diseases, or the latest research and results)!

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