Obesity and cardiovascular disease
Obesity and cardiovascular disease
Ginagamit ito bilang biologically active na pampadagdag sa pagkain — dagdag na pinagmumulan ng mga bitamina — B2, B6, C, mga organikong asido — mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6.
ЧИТАТЬ ДАЛЕЕ ...
Obesity and cardiovascular disease: A critical connection Obesity, as a pathologically increased percentage of body fat, defined as having a Body Mass Index (BMI) of ≥30 kg/m 2 represents a worldwide increasing health problem. Numerous studies have shown a close connection between obesity and an increased risk for cardiovascular disease (CVD), including coronary heart disease (CHD), congestive heart failure, stroke, and arterial hypertension. Pathophysiological Mechanisms The connection between obesity and CVD is mediated by multiple pathophysiological processes: Metabolic Syndrome. Obesity is often associated with insulin resistance, impaired glucose tolerance, dyslipidemia (elevated triglycerides, low HDL-cholesterol), and hypertension. These factors, together with the so-called metabolic syndrome, which increases the cardiovascular risk is significant form. Inflammatory reactions. Adipöses tissue, in particular visceral fat, acts as an endocrine-active Organ and secretes Pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and Interleukin‑6 (IL‑6). Chronic inflammatory processes promote atherosclerosis formation. Endothelial dysfunction. Adipocytes influence the production of Adipozytokinen (e.g., Adiponectin, Leptin), which leads to disruption of the vascular endothelial function and vasodilation is impaired. Mechanical Stress. Increased body weight increases the work load of the heart, which can lead to left ventricular hypertrophy, and later of heart failure. Epidemiological Data According to the WHO estimates, over 650 million adults worldwide suffer from obesity. Epidemiological studies show: An increase in BMI of 5 kg/m 2 is associated with a doubling of the risk for coronary heart disease. In obese patients, the risk of stroke is increased by 40-60%. Obesity is associated in 70% of cases with arterial hypertension. Clinical Implications A weight reduction of 5-10% of initial body weight results in obese persons to a significant improvement in metabolic parameters: Lowering blood pressure Normalization of blood glucose levels Improvement of the lipid profile Reduction of inflammatory markers Prevention and therapy A multimodal approach for the prevention and treatment of obesity-associated cardiovascular diseases is essential: Diet: low-calorie, fiber-rich diet with a reduced content of saturated fatty acids and sugar. Movement therapy: at least 150 minutes of moderate physical activity per week. Drug therapy: in case of increased cardiovascular risk drugs for lowering blood pressure, lowering cholesterol or blood sugar control is necessary. Bariatric surgery for severe obesity (BMI≥40 kg/m 2 ) or BMI≥35 kg/m 2 with co-morbidities, the operating weight reduction in life can have the effect of increasing. Conclusion Obesity is disease a major, modifiable risk factor for cardiovascular disease. The early identification of obese patients, and a targeted Intervention for weight reduction can reduce the cardiovascular risk and the quality of life and life expectancy improve. Interdisciplinary care is of paramount importance.
Ang Cardio Balance Kapseln ay isang epektibo at ligtas na paraan para mapanatili ang kalusugan ng puso at pababain ang presyon ng dugo. Dahil sa kanilang natural na sangkap at mataas na bisa, nagiging maaasahang katuwang sila sa paglaban sa mataas na presyon ng dugo at sa pagpapabuti ng kalidad ng buhay. Obesity and cardiovascular disease.
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Ginagamit ito bilang biologically active na pampadagdag sa pagkain — dagdag na pinagmumulan ng mga bitamina — B2, B6, C, mga organikong asido — mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6. Cardio Balance helps reduce blood fat levels by reducing the production of cholesterol and triglycerides in the body and improving the transportation of fats in the bloodstream.
Of Moxonidine for hypertension: A possible therapy principle High blood pressure, known medically as hypertension, is one of the most common health challenges of the modern society. Studies show that millions of people suffer from this disease, which, if you will, if left untreated, serious complications such as heart attack, stroke, or kidney damage can result. In the search for effective treatment options Moxonidine comes into play — a drug that wins in the last years more and more important. What Moxonidine is? Moxonidine is an antihypertensive drug that belongs to the group of centrally acting antihypertensive agents. It is the so‑called I₁-imidazoline receptors) selectively acting on certain receptors in the brain (making it reduces the activity of the sympatheticus. The vessels in relaxation of the blood, thus Reducing the blood pressure. In contrast to other antihypertensive agents Moxonidine shows a relatively favorable side-effect profile, which makes its use for many patients, attractive. When Moxonidine is prescribed? Doctors prescribe Moxonidine typically: mild-to-moderate hypertension; in patients who do not respond to other medications for blood pressure bad or not tolerated; in combination therapies, when a single medication is not sufficient to keep the blood pressure stable. Particularly valuable Moxonidine in patients with additional risk factors such as Obesity or metabolic disorders, as it can affect the insulin sensitivity, positive, and thus, the metabolism improves. Advantages of Moxonidine Most of the studies highlight the following advantages: Good compatibility: compared to older antihypertensive substances occur drowsiness or dizziness‑ like symptoms less frequently. Metabolic advantages: It can reduce insulin resistance and is therefore suitable for patients with Diabetes or pre-diabetes of interest to you. Long-term effectiveness: Regular intake leads to a stable blood pressure over the course of the day. Potential Side Effects In spite of its good tolerability, Moxonidine may cause, like any medicine, side effects. The most common include: Headache; Fatigue; Dry mouth; Dizziness, especially at the beginning of treatment. In rare cases, it can also lead to heart rhythm disorders, or allergic reactions. Therefore, the intake should always be done under medical supervision. Conclusion Moxonidine offers a promising Option in the treatment of hypertension, especially for patients in whom conventional therapies are pushed to their limits. It is an effective blood combined pressure reduction with a favorable metabolic profile, and an overall good tolerability. However, it is important that the therapy is always tailored and checked regularly. The decision to regulation should always meet with a physician who takes into account the overall situation of the patient. Healthy lifestyle, balanced diet and regular physical activity are the most important cornerstone for the prevention and long-time control of high blood pressure, regardless of whether drugs are used or not. Would you like me to make a certain section in more detail, or to add more information about an aspect?